Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays
نویسندگان
چکیده
Funding: we thank the Parker Hughes Fund and National Institutes of Health for grants for supporting this study. DN is supported by a research grant from the Deutsche Forschungsgemeinschaft (DFG, NO 817/1-1), NK is supported by a fellowship from the Tower Cancer Research Foundation. HPK holds the Mark Goodson Chair in Oncology Research at Cedars Sinai Medical Center and is a member of the Jonsson Cancer Center and the Molecular Biology Institute of UCLA. This work was also supported by grant-in-aid from the Department of Health, Welfare and Labor and from MEXT of the Japanese government.
منابع مشابه
Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy.
BACKGROUND T-cell prolymphocytic leukemia is a rare aggressive lymphoproliferative disease with a mature T-cell phenotype and characteristic genomic lesions such as inv(14)(q11q34), t(14;14)(q11;q32) or t(X;14)(q28;q11), mutation of the ATM gene on chromosome 11 and secondary alterations such as deletions of chromosome 8p and duplications of 8q. DESIGN AND METHODS We analyzed malignant cells ...
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